eN-LNP is a fully automated, standalone microfluidic platform built to rapidly formulate and characterize lipid nanoparticles. Designed around an industry-standard 96-well format, the system integrates advanced microfluidic mixing to deliver precise, tunable control over LNP synthesis. By allowing users to easily adjust inlet numbers, positions, diameters, and individual flow rates via an intuitive graphical user interface, eN-LNP dramatically accelerates formulation development and process optimization.

Scalable Production Architecture

• Versatile Flow Control: A robust, pressure-driven fluidic architecture supports a continuous operating range from microliter-scale screening up to larger-volume production.

• Chemically Robust Design: Constructed using optimized 3D-printing methods, the microfluidic modules are highly durable, cost-effective, and fully compatible with the aggressive solvents required in modern biopharmaceutical applications.

Inline Characterization & Analytics

• Seamless Module Integration: The high-throughput synthesis device directly interfaces with inline solvent separation and modification modules.

• Direct Analytical Readout: Enables immediate characterization of particle size, polydispersity index (PDI), and composition using standard DLS, UV/Vis, and IR plate readers without requiring offline sample transfer.